Your privacy, your choice

We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media.

By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with varying standards of data protection.

See our privacy policy for more information on the use of your personal data.

for further information and to change your choices.
Skip to main content
Fig. 5 | Molecular Autism

Fig. 5

From: Modeling the neuropsychiatric manifestations of Lowe syndrome using induced pluripotent stem cells: defective F-actin polymerization and WAVE-1 expression in neuronal cells

Fig. 5

a. Immunocytochemistry showing WAVE-1 expression pattern in NPCs. The control samples (LS200, 400 and 600; 690C) show a robust staining pattern with localization to the cytoskeleton. In the patient samples (LS100, 300 and 500), expression is patchy and large inclusions are seen. Inclusions are not seen in the 690KO line. The WAVE-1 inclusions were observed in duplicate NPC samples. b. WAVE-1 expression by quantitative immunocytochemistry. Differences between control and patient samples were not statistically significant using Student’s t test, two-tailed. Error bars are standard deviations

Back to article page

Molecular Autism

ISSN: 2040-2392