Fig. 6
From: Chd8 haploinsufficiency impairs early brain development and protein homeostasis later in life
Clustering of differentially expressed genes by temporal patterns. (Left) Heatmaps show clustering of the union set of differentially expressed genes (n = 853 total), plotting standardized log2 fold-changes. (Middle) Line plots show the change in log2 fold-change over time for all genes in the cluster, colored by Pearson correlation to the centroid of the cluster. (Right) Barplots of the − log10 adjusted p value of selected pathways significantly associated with genes in each cluster