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Fig. 5 | Molecular Autism

Fig. 5

From: Ribosome profiling in mouse hippocampus: plasticity-induced regulation and bidirectional control by TSC2 and FMRP

Fig. 5

Some mRNAs altered in unstimulated Tsc2+/− slices do not respond to DHPG-mGluR signaling. a, b Venn diagrams showing overlap between Tsc2+/− dysregulated RNAs and DHPG-responsive RNAs (a) and Tsc2+/− dysregulated RPFs and DHPG-responsive RPFs (b). Gene overlap test was performed using Fisher’s exact test and a background size of expressed RNAs used in DE analysis. c, d Heat maps of mRNAs (c) and RPFs (d) that overlap from (a) and (b). Relative gene expression is shown, and each column represents a biological replicate of littermates (n = 3)

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Molecular Autism

ISSN: 2040-2392