Your privacy, your choice

We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media.

By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with varying standards of data protection.

See our privacy policy for more information on the use of your personal data.

for further information and to change your choices.
Skip to main content
Fig. 5 | Molecular Autism

Fig. 5

From: Cortex-restricted deletion of Foxp1 impairs barrel formation and induces aberrant tactile responses in a mouse model of autism

Fig. 5

Foxp1 regulates barrel formation in S1. A and B Brain coronal sections from P7 WT and Foxp1-cKO mice subjected to VGluT2 (A) or 5-HT (B) immunostaining. Arrow delineates the barrel units in layer IV of S1. The barrel patches from TCA were almost invisible in Foxp1-cKO mice. Scale bar, 200 μm in (A) and (B). C and D Quantifications of VGluT2 (A) and 5-HT (B) fluorescence intensity of layer IV. Circles represent the average fluorescence intensity for each animal (3 animals per genotype; 3 sections per animal). ***p < 0.001. E A representative image showing 5-HT staining on flattened cortices from P7 WT and Foxp1-cKO mice. Scale bar, 200 μm

Back to article page

Molecular Autism

ISSN: 2040-2392