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Fig. 3 | Molecular Autism

Fig. 3

From: Genetic and phenotypic heterogeneity in early neurodevelopmental traits in the Norwegian Mother, Father and Child Cohort Study

Fig. 3

Estimated effects of factors from the correlated factor model in a multivariate regression controlling for the effects of all factors on the outcome for 5 selected diagnostic outcomes. Effects are presented as odds ratios calculated from the exponential of the standardized beta value from the logistic regression in the measurement models. 95% percent confidence intervals are shown. Due to high correlations amongst domains in the broad areas of social communication (the language & verbal communication, nonverbal communication and joint attention, play, and social attention and interest factors), ADHD-associated traits (the inattention and overactivity, waiting, impulsivity factors), and repetitive and restricted behaviors (the repetitive and idiosyncratic speech and repetitive and restricted behaviors and interests factors) effects of these factors were constrained to be equal to avoid collinearity issues. “*”, “**”, “***” denote adjusted p < 0.05, < 0.01, and < 0.001 respectively, after multiple testing correction. For full results of the outcome models, see the supplementary results (Additional file 2)

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Molecular Autism

ISSN: 2040-2392