Developmental trajectories in infants and pre-school children with Neurofibromatosis 1

Table 4 Linear mixed modelling F statistic and p values of fixed effects for MSEL, VABS AND CBCL

	MSEL: Visual Reception			Fine Motor			Receptive Language			Expressive Language			Early Learning Composite
	df	F	p	df	F	p	df	F	p	df	F	p	df	F	p
Intercept	1, 56	3567.94	< .001*	1,53	1786.79	< .001*	1, 53	3036.60	< .001*	1, 56	2590.40	< .001*	1, 53	4364.92	< .001*
Group	1, 56	84.72	< .001*	1,53	64.16	< .001*	1, 53	111.37	< .001*	1, 57	36.59	< .001*	1, 53	85.30	< .001*
Timepoint	4, 178	38.46	< .001*	4, 174	7.11	< .001*	4, 177	53.75	< .001*	4, 179	19.57	< .001*	4, 170	61.97	< .001*
Sex	1, 54	0.18	.676	1, 51	0.17	.679	1, 50	0.38	.541	1, 54	1.33	.254	1, 51	0.20	.657
Group x Timepoint	4, 178	30.83	< .001*	4, 174	13.65	< .001*	4, 177	23.51	< .001*	4, 179	20.03	< .001*	4, 170	41.30	< .001*

	VABS: Communication			Daily Living Skills			Socialization			Motor Skills			Vineland Adaptive Behaviour Composite
	df	F	p	df	F	p	df	F	p	df	F	p	df	F	p
Intercept	1, 50	7107.57	< .001*	1, 55	8034.63	< .001*	1, 59	7396.78	< .001*	1, 54	5814.12	< .001*	1, 57	6986.46	< .001*
Group	1, 50	14.15	< .001*	1, 55	5.60	.022*	1, 59	2.02	.160	1, 54	22.55	< .001*	1, 57	13.92	< .001*
Timepoint	4, 148	10.97	< .001*	4, 156	9.57	< .001*	4, 150	3.72	.006*	4, 149	12.24	< .001*	4, 143	8.24	< .001*
Sex	1, 48	1.39	.245	1, 53	1.84	.180	1, 58	2.34	.132	1, 53	.52	.475	1, 56	2.29	.136
Group x Timepoint	4, 148	6.78	< .001*	4, 156	3.95	.004*	4, 150	5.31	< .001*	4, 149	2.65	.035*	4, 143	8.22	< .001*

Maternal education was included in all models as a covariate. df = degrees of freedom, F statistic, p value, * = significant results

ISSN: 2040-2392