Table 1 Developmental milestones
Develomental Milestones | Nesting | Genotype | P2 | P4 | P6 | P8 | P10 | P12 | P14 |
|---|---|---|---|---|---|---|---|---|---|
Body Length (cm) | SN | WT | 5.26 ± 0.06 | 5.82 ± 0.07 | 6.35 ± 0.06 | 6.85 ± 0.08 | 7.16 ± 0.06 | 7.59 ± 0.07 | 8.02 ± 0.08 |
###,***,§§§ |  | HET | 5.34 ± 0.08 | 5.88 ± 0.07 | 6.39 ± 0.06 | 6.86 ± 0.08 | 7.21 ± 0.07 | 7.64 ± 0.08 | 8.06 ± 0.09 |
|  |  | KO | 5.40 ± 0.07 | 5.85 ± 0.07 | 6.16 ± 0.06 | 6.46 ± 0.07 | 6.63 ± 0.06 | 6.92 ± 0.10 | 7.25 ± 0.09 |
|  | CN | WT | 5.16 ± 0.06 | 5.82 ± 0.07 | 6.31 ± 0.06 | 6.80 ± 0.09 | 7.27 ± 0.08 | 7.58 ± 0.09 | 8.06 ± 0.08 |
|  |  | HET | 5.26 ± 0.07 | 5.83 ± 0.06 | 6.27 ± 0.04 | 6.88 ± 0.08 | 7.29 ± 0.07 | 7.58 ± 0.07 | 8.00 ± 0.05 |
|  |  | KO | 5.26 ± 0.06 | 5.64 ± 0.05 | 5.98 ± 0.04 | 6.24 ± 0.05 | 6.49 ± 0.06 | 6.71 ± 0.05 | 6.94 ± 0.05 |
Pinnae Detachment (n) | SN | WT | 1.13 ± 0.26 | 2.00 ± 0.00 | 1.88 ± 0.09 | 2.00 ± 0.00 | 2.00 ± 0.00 | 2.00 ± 0.00 | 2.13 ± 0.09 |
###, + ,$$$ |  | HET | 0.61 ± 0.20 | 1.89 ± 0.08 | 1.78 ± 0.10 | 1.94 ± 0.06 | 2.00 ± 0.00 | 2.00 ± 0.00 | 2.28 ± 0.11 |
|  |  | KO | 0.84 ± 0.22 | 1.68 ± 0.11 | 1.68 ± 0.11 | 1.79 ± 0.10 | 2.00 ± 0.00 | 2.00 ± 0.00 | 2.05 ± 0.05 |
|  | CN | WT | 0.25 ± 0.18 | 2.00 ± 0.00 | 1.92 ± 0.08 | 2.00 ± 0.00 | 2.00 ± 0.00 | 2.00 ± 0.00 | 2.00 ± 0.00 |
|  |  | HET | 0.17 ± 0.11 | 1.92 ± 0.08 | 1.83 ± 0.11 | 2.00 ± 0.00 | 2.00 ± 0.00 | 2.00 ± 0.00 | 2.08 ± 0.08 |
|  |  | KO | 0.06 ± 0.06 | 1.88 ± 0.08 | 1.88 ± 0.08 | 1.94 ± 0.06 | 2.00 ± 0.00 | 2.00 ± 0.00 | 2.00 ± 0.00 |
Eye Opening (n) | SN | WT | 1.00 ± 0.00 | 1.00 ± 0.00 | 1.00 ± 0.00 | 1.00 ± 0.00 | 1.00 ± 0.00 | 1.19 ± 0.10 | 1.88 ± 0.09 |
###, ***, §§§ |  | HET | 1.00 ± 0.00 | 1.00 ± 0.00 | 1.00 ± 0.00 | 1.06 ± 0.06 | 1.06 ± 0.06 | 1.11 ± 0.08 | 1.83 ± 0.09 |
|  |  | KO | 1.00 ± 0.00 | 1.00 ± 0.00 | 1.00 ± 0.00 | 1.00 ± 0.00 | 1.00 ± 0.00 | 1.00 ± 0.00 | 1.37 ± 0.11 |
|  | CN | WT | 1.00 ± 0.00 | 1.00 ± 0.00 | 1.00 ± 0.00 | 1.00 ± 0.00 | 1.00 ± 0.00 | 1.00 ± 0.00 | 1.83 ± 0.11 |
|  |  | HET | 1.00 ± 0.00 | 1.00 ± 0.00 | 1.00 ± 0.00 | 1.00 ± 0.00 | 1.00 ± 0.00 | 1.00 ± 0.00 | 1.92 ± 0.08 |
|  |  | KO | 1.00 ± 0.00 | 1.00 ± 0.00 | 1.00 ± 0.00 | 1.00 ± 0.00 | 1.00 ± 0.00 | 1.00 ± 0.00 | 1.59 ± 0.12 |
Incisor Eruption (n) | SN | WT | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.19 ± 0.10 | 1.56 ± 0.20 | 2.00 ± 0.00 | 2.00 ± 0.00 |
### |  | HET | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.22 ± 0.13 | 1.39 ± 0.20 | 2.00 ± 0.00 | 2.00 ± 0.00 |
|  |  | KO | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.32 ± 0.15 | 1.63 ± 0.16 | 2.00 ± 0.00 | 2.00 ± 0.00 |
|  | CN | WT | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.17 ± 0.11 | 2.00 ± 0.00 | 2.00 ± 0.00 | 2.00 ± 0.00 |
|  |  | HET | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 1.50 ± 0.23 | 2.00 ± 0.00 | 2.00 ± 0.00 |
|  |  | KO | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 1.65 ± 0.19 | 2.00 ± 0.00 | 2.00 ± 0.00 |
Fur Development (n) | SN | WT | 0.00 ± 0.00 | 0.34 ± 0.06 | 0.72 ± 0.10 | 1.47 ± 0.10 | 2.25 ± 0.11 | 2.81 ± 0.06 | 3.00 ± 0.00 |
###, $$$ |  | HET | 0.00 ± 0.00 | 0.39 ± 0.05 | 0.69 ± 0.09 | 1.56 ± 0.04 | 2.39 ± 0.09 | 2.94 ± 0.04 | 3.00 ± 0.00 |
|  |  | KO | 0.00 ± 0.00 | 0.45 ± 0.04 | 0.74 ± 0.10 | 1.55 ± 0.08 | 2.34 ± 0.08 | 2.76 ± 0.06 | 2.97 ± 0.03 |
|  | CN | WT | 0.04 ± 0.04 | 0.42 ± 0.06 | 0.92 ± 0.14 | 1.54 ± 0.04 | 2.50 ± 0.00 | 2.83 ± 0.07 | 3.00 ± 0.00 |
|  |  | HET | 0.00 ± 0.00 | 0.46 ± 0.04 | 1.00 ± 0.14 | 1.67 ± 0.07 | 2.55 ± 0.05 | 2.88 ± 0.07 | 3.00 ± 0.00 |
|  |  | KO | 0.00 ± 0.00 | 0.38 ± 0.05 | 0.88 ± 0.12 | 1.59 ± 0.07 | 2.35 ± 0.09 | 2.68 ± 0.06 | 2.97 ± 0.03 |
Milk Spot (n) | SN | WT | 3.00 ± 0.00 | 2.81 ± 0.14 | 2.94 ± 0.06 | 2.50 ± 0.13 | 2.00 ± 0.20 | 0.69 ± 0.18 | 0.06 ± 0.06 |
###, §§§, $ |  | HET | 2.89 ± 0.11 | 2.94 ± 0.06 | 3.00 ± 0.00 | 2.72 ± 0.11 | 2.11 ± 0.16 | 0.67 ± 0.16 | 0.00 ± 0.00 |
|  |  | KO | 2.89 ± 0.11 | 2.79 ± 0.14 | 2.89 ± 0.07 | 2.58 ± 0.14 | 2.16 ± 0.19 | 1.21 ± 0.25 | 0.26 ± 0.13 |
|  | CN | WT | 3.00 ± 0.00 | 2.92 ± 0.08 | 2.83 ± 0.11 | 2.00 ± 0.37 | 1.25 ± 0.37 | 0.67 ± 0.14 | 0.00 ± 0.00 |
|  |  | HET | 3.00 ± 0.00 | 3.00 ± 0.00 | 3.00 ± 0.00 | 2.42 ± 0.34 | 1.58 ± 0.38 | 0.75 ± 0.18 | 0.00 ± 0.00 |
|  |  | KO | 2.94 ± 0.06 | 2.53 ± 0.21 | 2.76 ± 0.18 | 2.12 ± 0.24 | 2.35 ± 0.17 | 1.47 ± 0.26 | 0.24 ± 0.11 |