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Fig. 1 | Molecular Autism

Fig. 1

From: Evolutionary constrained genes associated with autism spectrum disorder across 2,054 nonhuman primate genomes

Fig. 1

A. Density histogram of the Residual Variation Intolerance Scores (RVIS) for SFARI ASD genes (blue, N = 729) and non-ASD (red, N = 17,437) genes. The RVIS scores are normalised and hence centre on a mean of 0. Delimiters on x-axis range from − 5.0 to 5.0. B. The descriptions are the same as A for the DISGENET ASD genes (blue, N = 793) and non-ASD (red, N = 17,373) genes. C. Box and whisker plots depicting the distribution of RVIS scores with median (red line) for SFARI ASD and non-ASD genes. Delimiters on x-axis range from − 1.5 to 1.5. *** P < 0.001 (t test). D. Same as C using the DisGenet ASD genes

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Molecular Autism

ISSN: 2040-2392