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Fig. 3 | Molecular Autism

Fig. 3

From: Evolutionary constrained genes associated with autism spectrum disorder across 2,054 nonhuman primate genomes

Fig. 3

A. Density histogram of the Residual Variation Intolerance Scores (RVIS) for DisGeNET schizophrenia (A), epilepsy (B) and intellectual disability (ID) genes (C) (coloured in blue) and non-disorder associated genes (red). The RVIS scores are normalised and hence centre on a mean of 0. Delimiters on x-axis range from − 5.0 to 5.0. B. The descriptions are the same as A. D-F. Box and whisker plots depicting the distribution of RVIS scores with median (red line) for schizophrenia (D), epilepsy (E) and ID (F) DisGeNET genes. Delimiters on x-axis range from − 1.5 to 1.5. *** P < 0.001 (t-test)

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Molecular Autism

ISSN: 2040-2392