Impact of chronic intranasal oxytocin administration on face expression processing in autistic children: a randomized controlled trial using fMRI

Table 2 Diagnostic-group comparison of the average face processing activity in each of the ROIs

ROI activity FACES vs. FIX contrast	Autism beta-value	No autism beta-value	Group comparison
ROI activity FACES vs. FIX contrast	Autism beta-value	No autism beta-value	t value	P_unc	P_FDR
V1	− 0.05	− 0.01	− 0.91	0.37	0.55
Left inferior occipital	0.16*	0.15*	0.37	0.71	0.78
Right inferior occipital	0.25*	0.20*	1.11	0.27	0.55
Left posterior fusiform	0.22*	0.17*	0.98	0.33	0.55
Right posterior fusiform	0.22*	0.26*	− 0.72	0.48	0.60
Left STS	0.01	0.06*	− 1.17	0.25	0.55
Right STS	0.06°	0.09*	− 0.81	0.42	0.57
Left amygdala	0.08	0.10*	− 0.31	0.76	0.78
Right amygdala	0.09*	0.08*	0.28	0.78	0.78
Left anterior temporal	0.00	0.07*	− 1.87	0.07	0.55
Right anterior temporal	0.00	0.05*	− 1.36	0.18	0.55
Left inferior frontal	0.02	0.06	− 1.13	0.26	0.55
Right inferior frontal	0.26*	0.18*	1.58	0.12	0.55

Beta-values with an asterisks (° p < 0.05 uncorrected, * q < 0.05 FDR corrected) indicate whether the FACESvsFIX contrast yields significant brain activity within a particular ROI within a particular group, based on a one-sample t-test with H₀: Mean X = 0. P-values in bold (p < 0.05) indicate whether the FACESvsFIX contrast yields significant brain activity within a particular ROI between both groups, based on a two-sample t-test. However, no significant group-differences were observed

ISSN: 2040-2392