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Articles

Page 13 of 17

  1. Findings of auditory abnormalities in children with autism spectrum disorder (ASD) include delayed superior temporal gyrus auditory responses, pre- and post-stimulus superior temporal gyrus (STG) auditory osci...

    Authors: J. Christopher Edgar, Charles L. Fisk IV, Jeffrey I. Berman, Darina Chudnovskaya, Song Liu, Juhi Pandey, John D. Herrington, Russell G. Port, Robert T. Schultz and Timothy P. L. Roberts
    Citation: Molecular Autism 2015 6:69
    Content type: Research Published on:

  2. Recent research investigating the extreme male brain theory of autism spectrum disorders (ASD) has drawn attention to the possibility that autistic type social difficulties may be associated with high prenatal...

    Authors: Manuela Barona, Radha Kothari, David Skuse and Nadia Micali
    Citation: Molecular Autism 2015 6:68
    Content type: Research Published on:

  4. Fragile X syndrome (FXS) is a neurodevelopmental disorder whose biochemical manifestations involve dysregulation of mGluR5-dependent pathways, which are widely modeled using cultured neurons. In vitro phenotyp...

    Authors: Daria Prilutsky, Alvin T. Kho, Nathan P. Palmer, Asha L. Bhakar, Niklas Smedemark-Margulies, Sek Won Kong, David M. Margulies, Mark F. Bear and Isaac S. Kohane
    Citation: Molecular Autism 2015 6:66
    Content type: Research Published on:

  5. Recent brain imaging findings suggest that there are widely distributed abnormalities affecting the brain connectivity in individuals with autism spectrum disorder (ASD). Using graph theoretical analysis, it i...

    Authors: Ulrika Roine, Timo Roine, Juha Salmi, Taina Nieminen-von Wendt, Pekka Tani, Sami Leppämäki, Pertti Rintahaka, Karen Caeyenberghs, Alexander Leemans and Mikko Sams
    Citation: Molecular Autism 2015 6:65
    Content type: Research Published on:

  6. Autism spectrum disorder (ASD) has been associated with autonomic atypicalities, although the nature of these differences remains largely unknown. Moreover, existing literature suggests large variability in au...

    Authors: Sakeena Panju, Jessica Brian, Annie Dupuis, Evdokia Anagnostou and Azadeh Kushki
    Citation: Molecular Autism 2015 6:64
    Content type: Research Published on:

  7. Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders characterized by impairment in social communication/interaction and inflexible/repetitive behavior. Several lines of evidence support g...

    Authors: Xin He, Stetson Thacker, Todd Romigh, Qi Yu, Thomas W. Frazier Jr and Charis Eng
    Citation: Molecular Autism 2015 6:63
    Content type: Research Published on:

    The Erratum to this article has been published in Molecular Autism 2016 7:14

  8. Aggression is common in patients with autism spectrum disorders (ASD) along with the core symptoms of impairments in social communication and repetitive behavior. Risperidone, an atypical antipsychotic, is wid...

    Authors: Emma L. Burrows, Liliana Laskaris, Lynn Koyama, Leonid Churilov, Joel C. Bornstein, Elisa L. Hill-Yardin and Anthony J. Hannan
    Citation: Molecular Autism 2015 6:62
    Content type: Research Published on:

  9. Individuals severely affected by autism spectrum disorder (ASD), including those with intellectual disability, expressive language impairment, and/or self-injurious behavior (SIB), are underrepresented in the ...

    Authors: Matthew Siegel, Kahsi A. Smith, Carla Mazefsky, Robin L. Gabriels, Craig Erickson, Desmond Kaplan, Eric M. Morrow, Logan Wink and Susan L. Santangelo
    Citation: Molecular Autism 2015 6:61
    Content type: Research Published on:

  10. The Duchenne and Becker muscular dystrophies (DMD, BMD) show significant comorbid diagnosis for autism, and the genomic sequences encoding the proteins responsible for these diseases, the dystrophin and associ...

    Authors: Rubén Miranda, Flora Nagapin, Bruno Bozon, Serge Laroche, Thierry Aubin and Cyrille Vaillend
    Citation: Molecular Autism 2015 6:60
    Content type: Research Published on:

  11. Theory-of-mind (ToM), the ability to infer people’s thoughts and feelings, is a pivotal skill in effective social interactions. Individuals with autism spectrum disorders (ASD) have been found to have altered ...

    Authors: Rajesh K. Kana, Jose O. Maximo, Diane L. Williams, Timothy A. Keller, Sarah E. Schipul, Vladimir L. Cherkassky, Nancy J. Minshew and Marcel Adam Just
    Citation: Molecular Autism 2015 6:59
    Content type: Research Published on:

  12. Previous studies have demonstrated aggregation of autistic traits in undiagnosed family members of children with autism spectrum disorder (ASD), which has significant implications for ASD risk in their offspri...

    Authors: Thomas W. Frazier, Eric A. Youngstrom, Antonio Y. Hardan, Stelios Georgiades, John N. Constantino and Charis Eng
    Citation: Molecular Autism 2015 6:58
    Content type: Research Published on:

  13. Platelets have been proven to be a useful cellular model to study some neuropathologies, due to the overlapping biological features between neurons and platelets as granule secreting cells. Altered platelet de...

    Authors: Nora Bijl, Chantal Thys, Christine Wittevrongel, Wouter De la Marche, Koenraad Devriendt, Hilde Peeters, Chris Van Geet and Kathleen Freson
    Citation: Molecular Autism 2015 6:57
    Content type: Research Published on:

  14. RBFOX1 (also known as FOX1 or A2BP1) regulates alternative splicing of a variety of transcripts crucial for neuronal functions. Physiological significance of RBFOX1 during brain development is seemingly essent...

    Authors: Nanako Hamada, Hidenori Ito, Ikuko Iwamoto, Rika Morishita, Hidenori Tabata and Koh-ichi Nagata
    Citation: Molecular Autism 2015 6:56
    Content type: Research Published on:

  15. Disruptive mutation in the CHD8 gene is one of the top genetic risk factors in autism spectrum disorders (ASDs). Previous analyses of genome-wide CHD8 occupancy and reduced expression of CHD8 by shRNA knockdown i...

    Authors: Ping Wang, Mingyan Lin, Erika Pedrosa, Anastasia Hrabovsky, Zheng Zhang, Wenjun Guo, Herbert M. Lachman and Deyou Zheng
    Citation: Molecular Autism 2015 6:55
    Content type: Research Published on:

  16. Autism spectrum disorder (ASD) is characterized by atypical development of cortical and subcortical gray matter volume. Subcortical structural changes have been associated with restricted and repetitive behavi...

    Authors: Ian W. Eisenberg, Gregory L. Wallace, Lauren Kenworthy, Stephen J. Gotts and Alex Martin
    Citation: Molecular Autism 2015 6:54
    Content type: Research Published on:

  17. Adolescent females with an autism spectrum disorder (ASD) are an understudied population, yet are also quite vulnerable, due to the increased complexities of social interaction and increased risk for internali...

    Authors: T. Rene Jamison and Jessica Oeth Schuttler
    Citation: Molecular Autism 2015 6:53
    Content type: Research Published on:

  19. Evidence indicates that social functioning deficits and sensory sensitivities in autism spectrum disorder (ASD) are related to atypical sensory integration. The exact mechanisms underlying these integration di...

    Authors: Katie Greenfield, Danielle Ropar, Alastair D. Smith, Mark Carey and Roger Newport
    Citation: Molecular Autism 2015 6:51
    Content type: Research Published on:

  20. Autism spectrum disorder (ASD) is diagnosed much less often in females than males. Emerging behavioral accounts suggest that the clinical presentation of autism is different in females and males, yet research ...

    Authors: Kaustubh Supekar and Vinod Menon
    Citation: Molecular Autism 2015 6:50
    Content type: Research Published on:

  21. Autism spectrum conditions (ASC) are a group of neurodevelopmental conditions characterized by difficulties in social interaction and communication alongside repetitive and stereotyped behaviours. ASC are heri...

    Authors: Varun Warrier, Vivienne Chee, Paula Smith, Bhismadev Chakrabarti and Simon Baron-Cohen
    Citation: Molecular Autism 2015 6:49
    Content type: Research Published on:

  22. Autism spectrum disorder (ASD) traits are continuously distributed throughout the population, and ASD symptoms are also frequently observed in patients with attention-deficit/hyperactivity disorder (ADHD). Bot...

    Authors: Eelco V. van Dongen, Daniel von Rhein, Laurence O’Dwyer, Barbara Franke, Catharina A. Hartman, Dirk J. Heslenfeld, Pieter J. Hoekstra, Jaap Oosterlaan, Nanda Rommelse and Jan Buitelaar
    Citation: Molecular Autism 2015 6:48
    Content type: Research Published on:

  23. Understanding and anticipating others’ mental or emotional states relies on the processing of social cues, such as dynamic facial expressions. Individuals with high-functioning autism (HFA) may process these c...

    Authors: Letizia Palumbo, Hollie G. Burnett and Tjeerd Jellema
    Citation: Molecular Autism 2015 6:47
    Content type: Research Published on:

  24. MicroRNAs are small RNA molecules that regulate the translation of protein from gene transcripts and are a powerful mechanism to regulate gene networks. Next-generation sequencing technologies have produced im...

    Authors: Michal Mor, Stefano Nardone, Dev Sharan Sams and Evan Elliott
    Citation: Molecular Autism 2015 6:46
    Content type: Research Published on:

  27. Autism spectrum disorder (ASD) is highly heritable, yet genome-wide association studies (GWAS), copy number variation screens, and candidate gene association studies have found no single factor accounting for ...

    Authors: Anthony J. Griswold, Nicole D. Dueker, Derek Van Booven, Joseph A. Rantus, James M. Jaworski, Susan H. Slifer, Michael A. Schmidt, William Hulme, Ioanna Konidari, Patrice L. Whitehead, Michael L. Cuccaro, Eden R. Martin, Jonathan L. Haines, John R. Gilbert, John P. Hussman and Margaret A. Pericak-Vance
    Citation: Molecular Autism 2015 6:43
    Content type: Research Published on:

  28. Male predominance is a prominent feature of autism spectrum disorders (ASD), with a reported male to female ratio of 4:1. Because of the overwhelming focus on males, little is known about the neuroanatomical b...

    Authors: Marie Schaer, John Kochalka, Aarthi Padmanabhan, Kaustubh Supekar and Vinod Menon
    Citation: Molecular Autism 2015 6:42
    Content type: Research Published on:

  29. The genetics of autism spectrum disorder (hereafter referred to as “autism”) are rapidly unfolding, with a significant increase in the identification of genes implicated in the disorder. Many of these genes ar...

    Authors: Neha Uppal, Rishi Puri, Frank Yuk, William G M Janssen, Ozlem Bozdagi-Gunal, Hala Harony-Nicolas, Dara L Dickstein, Joseph D Buxbaum and Patrick R Hof
    Citation: Molecular Autism 2015 6:41
    Content type: Research Published on:

  30. There is growing research evidence that subclinical autistic traits are elevated in relatives of individuals with autism spectrum disorder (ASD), continuously distributed in the general population and likely t...

    Authors: I. Magiati, D. A. Goh, S. J. Lim, D. Z. Q. Gan, J. C. L. Leong, C. Allison, S. Baron-Cohen, A. Rifkin-Graboi, B F P. Broekman, S-M. Saw, Y-S. Chong, K. Kwek, P. D. Gluckman, S. B. Lim and M. J. Meaney
    Citation: Molecular Autism 2015 6:40
    Content type: Research Published on:

  33. Autism spectrum disorders (ASDs) likely involve dysregulation of multiple genes related to brain function and development. Abnormalities in individual regulatory small non-coding RNA (sncRNA), including microR...

    Authors: Bradley P. Ander, Nicole Barger, Boryana Stamova, Frank R. Sharp and Cynthia M. Schumann
    Citation: Molecular Autism 2015 6:37
    Content type: Research Published on:

  34. One of the most consistent findings in autism spectrum disorder (ASD) research is a higher rate of ASD diagnosis in males than females. Despite this, remarkably little research has focused on the reasons for t...

    Authors: Alycia K Halladay, Somer Bishop, John N Constantino, Amy M Daniels, Katheen Koenig, Kate Palmer, Daniel Messinger, Kevin Pelphrey, Stephan J Sanders, Alison Tepper Singer, Julie Lounds Taylor and Peter Szatmari
    Citation: Molecular Autism 2015 6:36
    Content type: Viewpoint Published on:

  36. The prevalence of autism spectrum disorders (ASDs) is higher in men than in women. The extreme male brain theory proposes that excessive prenatal testosterone activity could be a risk factor for ASDs. However,...

    Authors: Yasuhiro Masuya, Yuko Okamoto, Keisuke Inohara, Yukiko Matsumura, Toru Fujioka, Yuji Wada and Hirotaka Kosaka
    Citation: Molecular Autism 2015 6:34
    Content type: Research Published on:

  37. Several observations support the hypothesis that differences in synaptic and regional cerebral plasticity between the sexes account for the high ratio of males to females in autism. First, males are more susce...

    Authors: Laurent Mottron, Pauline Duret, Sophia Mueller, Robert D Moore, Baudouin Forgeot d’Arc, Sebastien Jacquemont and Lan Xiong
    Citation: Molecular Autism 2015 6:33
    Content type: Review Published on:

  38. The increased male prevalence of autism spectrum disorder (ASD) may be mirrored by the early emergence of sex differences in ASD symptoms and cognitive functioning. The female protective effect hypothesis posi...

    Authors: Daniel S. Messinger, Gregory S. Young, Sara Jane Webb, Sally Ozonoff, Susan E. Bryson, Alice Carter, Leslie Carver, Tony Charman, Katarzyna Chawarska, Suzanne Curtin, Karen Dobkins, Irva Hertz-Picciotto, Ted Hutman, Jana M. Iverson, Rebecca Landa, Charles A. Nelson…
    Citation: Molecular Autism 2015 6:32
    Content type: Research Published on:

  40. Previous autism research has hypothesized that abnormalities of functional connectivity in autism spectrum disorder (ASD) may vary with the spatial distance between two brain regions. Although several resting-...

    Authors: Takashi Itahashi, Takashi Yamada, Hiromi Watanabe, Motoaki Nakamura, Haruhisa Ohta, Chieko Kanai, Akira Iwanami, Nobumasa Kato and Ryu-ichiro Hashimoto
    Citation: Molecular Autism 2015 6:30
    Content type: Research Published on:

  41. Neuroanatomical differences between individuals with and without autism spectrum disorder (ASD) were inconsistent in the literature. Such heterogeneity may substantially originate from age-differential effects.

    Authors: Hsiang-Yuan Lin, Hsing-Chang Ni, Meng-Chuan Lai, Wen-Yih Isaac Tseng and Susan Shur-Fen Gau
    Citation: Molecular Autism 2015 6:29
    Content type: Research Published on:

  42. The anterior cingulate cortex (ACC) is a brain area involved in modulating behavior associated with social interaction, disruption of which is a core feature of autism spectrum disorder (ASD). Functional brain...

    Authors: Michelle J Chandley, Jessica D Crawford, Attila Szebeni, Katalin Szebeni and Gregory A Ordway
    Citation: Molecular Autism 2015 6:28
    Content type: Research Published on:

    The Erratum to this article has been published in Molecular Autism 2015 6:38

  43. Autism spectrum disorders (ASDs) are more prevalent in males, suggesting a multiple threshold liability model in which females are, on average, protected by sex-differential mechanisms. Under this model, autis...

    Authors: Donna M Werling and Daniel H Geschwind
    Citation: Molecular Autism 2015 6:27
    Content type: Research Published on:

  44. Abnormalities in the corpus callosum have been reported in individuals with autism spectrum disorder (ASD), but few studies have evaluated young children. Sex differences in callosal organization and diffusion...

    Authors: Christine Wu Nordahl, Ana-Maria Iosif, Gregory S Young, Lee Michael Perry, Robert Dougherty, Aaron Lee, Deana Li, Michael H Buonocore, Tony Simon, Sally Rogers, Brian Wandell and David G Amaral
    Citation: Molecular Autism 2015 6:26
    Content type: Research Published on:

    The Erratum to this article has been published in Molecular Autism 2015 6:39

  45. A 4:1 male to female sex bias has consistently been observed in autism spectrum disorder (ASD). Epidemiological and genetic studies suggest a female protective effect (FPE) may account for part of this bias; h...

    Authors: Jake Gockley, A Jeremy Willsey, Shan Dong, Joseph D Dougherty, John N Constantino and Stephan J Sanders
    Citation: Molecular Autism 2015 6:25
    Content type: Research Published on:

  47. Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by significant impairment in reciprocal social interactions and communication coupled with stereotyped, repetitive behaviors and r...

    Authors: Valerie W Hu, Tewarit Sarachana, Rachel M Sherrard and Kristen M Kocher
    Citation: Molecular Autism 2015 6:7
    Content type: Research Published on:

  49. SHANK proteins are crucial for the formation and plasticity of excitatory synapses. Although mutations in all three SHANK genes are associated with autism spectrum disorder (ASD), SHANK3 appears to be the major A...

    Authors: Daniela M Cochoy, Alexander Kolevzon, Yuji Kajiwara, Michael Schoen, Maria Pascual-Lucas, Stacey Lurie, Joseph D Buxbaum, Tobias M Boeckers and Michael J Schmeisser
    Citation: Molecular Autism 2015 6:23
    Content type: Research Published on:

  50. Difficulties in recognizing emotions and mental states are central characteristics of autism spectrum conditions (ASC). However, emotion recognition (ER) studies have focused mostly on recognition of the six ‘...

    Authors: Ofer Golan, Yana Sinai-Gavrilov and Simon Baron-Cohen
    Citation: Molecular Autism 2015 6:22
    Content type: Research Published on:
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Molecular Autism

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